Benzodiazepines - BZO

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Glossary: Benzodiazepines - BZO


Benzodiazepines
BZO

Screening Cut-off: 300 ng/ml
DEA Drug Class: Depressant
Type: Prescription Drug
Trade Names: Alprazolam Intensol, Alti-Alprazolam, Alti-Bromazepam, Alti-Clonazepam, Alti-Triazolam, Apo-Alpraz, Apo-Chlordiazepoxide, Apo-Clonazepam, Apo-Clorazepate, Apo-Diazepam, Apo-Flurazepam, Apo-Lorazepam, Apo-Oxazepam, Apo-Temazepam, Apo-Triazo, Ativan, Clonapam, Clonopin, Dalmane, Diastat, Diazemuls, Diazepam Intensol, Dizac, Doral, Frisium, Gen-Alprazolam, Gen-Bromazepam, Gen-Clonazepam, Gen-Triazolam, Halcion, Klonopin, Lectopam, Librium, Lorazepam Intensol, Mogadon, Niravam, Novo-Alprazol, Novo-Clopate, Novo-Dipam, Novo-Flupam, Novo-Lorazem, Novo-Poxide, Novo-Temazepam, Novo-Triolam, Novoxapam, Nu-Alpraz, Nu-Loraz, Paxipam 0, Pms-Clonazepam, Pms-Diazepam, Prosom, Restoril, Rivotril, Rohypnol, Serax, Somnol, T-Tab, Tranxene, Tranxene-Sd, Tranxene-Sd Half Strength, Valium, Xanax
Street Names:  Downer, Downs, Nerve Pills, Roofies, R-2, Tranks

Drug Information

Benzodiazepines (BZO) are medications that are frequently prescribed for the symptomatic treatment of anxiety and sleep disorders. They produce their effects via specific receptors involving a neurochemical called gamma aminobutyric acid (GABA). Because they are safer and more effective, Benzodiazepines have replaced barbiturates in the treatment of both anxiety and insomnia. Benzodiazepines are also used as sedatives before some surgical and medical procedures, and for the treatment of seizure disorders and alcohol withdrawal. Risk of physical dependence increases if Benzodiazepines are taken regularly (e.g., daily) for more than a few months, especially at higher than normal doses. Stopping abruptly can bring on such symptoms as trouble sleeping, gastrointestinal upset, feeling unwell, loss of appetite, sweating, trembling, weakness, anxiety and changes in perception. Only trace amounts (less than 1%) of most Benzodiazepines are excreted unaltered in the urine; most of the concentration in urine is conjugated drug. The detection period for the Benzodiazepines in the urine is 3-7 days.

Drug Enforcement Agency (DEA) Drug Classification and Effects Information

  • Classification/Schedule III: Drugs with less abuse potential than schedule II; have moderate to low physical dependency, but may have high psychological dependence
  • Physical Dependency: Moderate
  • Psychological Dependency: Moderate
  • Tolerance: Yes
  • Possible Effects: Slurred speech, disorientation, drunken behavior without odor of alcohol, impaired memory of events, interacts with alcohol
  • Effects of Overdose: Shallow respiration, clammy skin, dilated pupils, weak and rapid pulse, coma, possible death
  • Withdrawal Syndrome: Anxiety, insomnia, tremors, delirium, convulsions, possible death

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