Buprenorphine - BUP

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Glossary: Buprenorphine - BUP


Buprenorphine
BUP

Screening Cut-off: 10 ng/ml
DEA Drug Class: Narcotic
Type: Prescription Drug
Trade Names: Buprenex, Suboxone, Subutex, Temgesic
Street Names: Bupe, Subbies, Temmies

Drug Information

Buprenorphine (BUP) is a prescription medication for people addicted to heroin or other opiates that acts by relieving the symptoms of opiate withdrawal such as agitation, nausea and insomnia. Buprenorphine is more weakly addictive and has a lower risk of overdose than methadone. The effects last for about three days.
Buprenorphine is sold under the brand name of Subutex and, in combination with naloxone, as Suboxone. Subutex is intended for use at the beginning of treatment while Suboxone is intended for the maintenance treatment of opiate addiction. (Naloxone was added to guard against intravenous abuse of buprenorphine by individuals physically dependent on opiates.) The side effects of buprenorphine include cold or flu-like symptoms, headaches, sweating, sleeping difficulties, nausea, and mood swings. Buprenorphine can cause dangerously diminished breathing, especially when used in combination with alcohol or other central nervous system depressants.

Drug Enforcement Agency (DEA) Drug Classification and Effects Information

  • Classification/Schedule III: Drugs with less abuse potential than schedule II; have moderate to low physical dependency, but may have high psychological dependence
  • Physical Dependency: High-Low
  • Psychological Dependency: High-Low
  • Tolerance: Yes
  • Possible Effects: Euphoria, drowsiness, respiratory depression, constricted pupils, nausea
  • Effects of Overdose: Slow and shallow breathing, clammy skin, convulsions, coma, possible death
  • Withdrawal Syndrome: Watery eyes, runny nose, yawning, loss of appetite, irritability, tremors, panic, cramps, nausea, chills and sweating

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